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Iraqi Journal of Biotechnology. 2004; 3 (1): 1-20
in English, Arabic | IMEMR | ID: emr-66224

ABSTRACT

Trials for gene therapy were conducted on dwarf mice by using germ cells and transgenic techniques. However; the integration of the growth gene within mice genomes have led to permanent expression and mice gigantism. With the move toward the using of somatic cells instead of germ cells, two approaches were available: 1-Ex vivo gene therapy. 2- In vivo gene therapy. This article is an overview on growth gene, growth hormone and future medical applications


Subject(s)
Animals, Laboratory , Growth Hormone , Genetic Therapy , Mice , Growth Hormone/physiology , Receptors, Somatotropin , Pituitary Gland/physiology
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